Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T)
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چکیده
منابع مشابه
Refractory anemia with ring sideroblasts associated with thrombocytosis (RARS-T).
A 75-year-old woman who was previously healthy was investigated for chronic anemia. Her hemoglobin was 94 g/L with a mean corpuscular volume of 108 fL, white cell counts were normal, and platelet count was high (480 3 10/L). Blood film showed marked red cell anisocytosis with dimorphic pattern, stomatocytes, no neutrophil dysplasia, and no blasts (panel A-B). Bone marrow aspirate smear demonstr...
متن کاملRefractory anemia with ring sideroblasts and thrombocytosis
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 58-year-old man presented with a 1-year history of transfusion-dependent anemia. On examination, he had pallor and his spleen was barely palpable. 9 /L. A blood differential count showed 40% neutrophils, 54% lymphocytes, 2% monocytes, and 3% eosinophils. A...
متن کاملHaematological and molecular responses in refractory anaemia with ring sideroblasts and thrombocytosis treated with lenalidomide.
To the Editor: Refractory anaemia with ring sideroblasts and thrombocytosis (RARS-T) is a rare entity and is defined as an overlap syndrome with clinical and morphologic features of both myelodysplastic syndrome (MDS) and BCR-ABL-negative myeloproliferative neoplasm, including marked thrombocytosis associated with abnormal megakaryocytes (1). Mutations in the Janus Kinase 2 gene (JAK2) and/or S...
متن کاملRefractory anemia with ring sideroblasts associated with marked thrombocytosis: case report and literature review.
"Refractory anemia with ring sideroblasts and thrombocytosis" (RARS-T) is a rare disease, a provisional entity, with a controversial status in the 2008 revised WHO classification. Even at present time, RARS-T is a matter of debate whether it is a distinct clinicopathological entity or more likely a constellation of clinical and pathological features of two well-defined myeloid neoplasms, myelod...
متن کاملClinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis.
BACKGROUND Refractory anemia with ring sideroblasts associated with marked thrombocytosis was proposed as a provisional entity in the 2001 World Health Organization classification of myeloid neoplasms and also in the 2008 version, but its existence as a single entity is contested. We wish to define the clinical features of this rare myelodysplastic/myeloproliferative neoplasm and to compare its...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2018
ISSN: 1768-3262
DOI: 10.4267/2042/68530